2, Singapore Center for 3D Printing, Singapore, , Singapore
Advancements in electronics are driving the biomedical field and vice-versa. Convergence of biomaterials and electronics holds promise for many applications and drives the field of bioelectronics. Last decade has seen emergence of high-performance, multi-functional, flexible and printed electronic devices that have contributed to the development of the new age, conformal and non-invasive biomedical devices. Bioelectronics platforms are gaining widespread attention as they provide a template to study the interactions between biological species and electronics.
The talk will highlight our group’s work on printed electronics using aerosol jet technology using various materials on different substrates. 3D bioprinting of biomaterials particularly hydrogels with cells will be discussed for various applications. We will also highlight our work on interfacing printed electronics and biomaterials for bioelectronic platforms for added functionality. The work showcases engaging 3D printing techniques to build bioelectronic platforms, and how 3D printing is driving the bio-medical industry with specifications such as user customization, cost-effectiveness and short response time. We report printing, optimizing and characterizing electronic circuits on bio-scaffolds/ biomaterials for making complete devices, thus trying to understand 3D printing capabilities for such platforms. We fabricated a freestanding and flexible hydrogel based platform using 3D bioprinting. The fabrication process is simple, easy and provides a flexible route to print materials with preferred shapes, size and spatial orientation. Through the design of interdigitated electrodes and heating coil, the platform can be tailored to print various circuits for different functionalities. The biocompatibility of the printed platform is tested using C2C12 murine myoblasts cell line. Furthermore, normal human dermal fibroblasts (primary cells) are also seeded on the platform to ascertain the compatibility. Thus, The fabricated bioelectronics platform is compatible with cells and tissues, cost-effective and does not require any post-processing. Our research is focused on bringing electronics and biomaterials together on a single platform for futuristic applications like drug delivery, wound management etc.