Over recent years there has been tremendous progress in developing low-temperature, solution-processible conjugated polymer semiconductors that provide high charge carrier mobilities for both n-type and p-type device operation, good operational stability and other functionalities such as efficient electroluminescene, sensing or memory functions for a variety of applications. We have been interested in a family of conjugated polymers that exhibit a low degree of energetic disorder owing to a well defined planar backbone conformation in their solid state. These polymers adopt a near amorphous microstructure but exhibit high carrier mobilities > 1 cm2/Vs. We are interested in understanding the charge transport and device physics of these materials and the relationship between molecular structure, microstructure and charge diffusion. In this talk we will review the current status of their technological applications, discuss state-of-the-art in device performance and discuss the physical processes that currently limit their performance and operational reliability and how these limitations may be overcome.