Mechanical cues regulate many aspects of biology, and we are developing materials capable of providing defined mechanical input to cells and tissues. Relevant signals include both resistance to cell intrinsic mechanical forces and application of extrinsic forces. These biomaterials can enhance the effectiveness of stem cell therapies, directly support and regenerate damaged tissues, and have led to bio-inspired new medical adhesives with unprecedented properties.
Faculty Member of the Wyss Institute. His laboratory designs biomaterials to make cell and protein therapies effective and practical
approaches to treat disease. He is a member of the National Academy of Engineering, the National Academy of Medicine, and the National
Academy of Inventors. He has won numerous awards, including the Clemson Award from the SFB, MERIT award from the NIH,
Distinguished Scientist Award from the IADR, Phi Beta Kappa Prize for Excellence in Undergraduate Teaching, and the Everett
Mendelsohn Excellence in Mentoring Award from Harvard College. His inventions have been licensed by numerous companies, leading to
commercialized products, and he is active on industrial scientific advisory boards.