Julian Lenis1 Francisco Bolívar Osorio1

1, University of Antioquia, Medellin, , Colombia

The diseases related to bone-muscular system are the most common cause of disability and affect hundreds of millions of people worldwide. This is a major challenge for the orthopedic industry, because they should produce implants that improve the quality of life of patients, minimize the incidence of complications and reduce hospital stays. To meet this need, researchers worldwide are working to find a way to produce implants for clinical use with high capacity for osseo-integration. These studies have led to the production and development of biocompatible materials as calcium phosphates, while being studied and refine constantly various deposition techniques for this biomaterial on metal substrates, but also of a good osseo-integration, currently they are looking substances that avoid the formation and proliferation of bacteria on the surface of these implants, thus disadvantaging the development of infections associated with them.

As implant material, titanium and titanium alloys has been widely used because of its excellent mechanical properties and bio-inert character. But, the metallic nature of these elements makes them highly susceptible to corrosion and wear when exposed to a biological environment, where there is rapid release of metal ions to the system and in addition to this, the lack of osteoinductivity generate very weak fixation of the implant, accompanied by the development generated by the adhesion of bacteria in the place where the material was implanted infections. To solve these problems have been studied a variety of surface modification techniques for metallic materials, some of which are chemical, physical and biological treatment methods.

Physical treatments involve processes such as depositing thin films on the surface of a metal substrate, in this case, it is biofunctionalized and provide antibacterial activity to the implant by incorporating composite coatings of silver - calcium phosphate obtained by RF magnetron sputtering.