Mohamed Eddaoudi1 2

1, King Abdullah University of Science and Technology, Thuwal, , Saudi Arabia
2, University of South Florida, Tampa, Florida, United States

Demand for functional materials targeted for specific applications is ever increasing as societal needs and demands mount with advancing technology. The building-block approach, whereby at the design stage the desired properties and functionality can be introduced in preselected molecular building blocks (MBBs) prior to the assembly process, has emerged as a prominent pathway for the rational construction of functional solid- state materials. One class of inorganic-organic hybrid materials, metal-organic frameworks (MOFs), has burgeoned in recent partly years due to effective design strategies (i.e. reticular chemistry) for their synthesis and their inherent [and readily interchangeable] hybrid, functional character. MOFs have emerged as a unique class of materials amenable to design and manipulation for desired function and application. Several design strategies have been utilized and developed to target viable MOF platforms, from the single-metal-ion molecular building block (MBB) approach to the hierarchical supermolecular building block and supermolecular building layer approaches (SBB and SBL, respectively). This inherent built-in information allows access to highly stabile and made-to-order porous materials toward applications pertaining to energy and environmental sustainability. Specifically, made-to-order MOFs addressing the energy-intensive separations, gas storage, and catalysis will be discussed