The development of organic bioelectronics has been intensified during last decade, in part sparked by several unique demonstrations of using the technology to bridge the signaling gap between biology and technology. Typically, thin film processing protocols, originally developed for large area electronics, have been explored to realize organic bioelectronic sensors and actuators. In order to distribute and reach target sites, such as in the nervous system for recording and/or stimulation, typically areal 2D device systems are not suitable.
Here, we report organic bioelectronics produced into fiber and capillary systems. The resulting technology defines a 1D filamentous organic bioelectronics platform, which makes penetration and definition of bioelectronics inside the biological system possible, at the same time limiting any damage caused to the nervous system, tissues and organs. Long range fibers and capillaries, extending over inches, have been developed with diameters ranging from 60 to 200 microns including semiconducting and electronic/ionic conductors to define device functionality for sensors and delivery devices. Different bioelectronic devices and distributed systems have been manufactured and applied to both animal and plant tissues to enable recording and stimulation of signaling and physiology at high spatiotemporal resolution with minimal bioelectronic “side effects”.