The Lithium-Sulfur (Li-S) batteries have been extensively investigated for next energy storage applications due to its great advantages such as much higher energy density and lower cost than current Lithium-ion batteries. Li-S batteries still suffer from several key performance issues (e.g., poor cycle life, self-discharge and rate capability) associated with polysulfide shuttling effect and slow kinetics. To tackle these problems, various approaches including the C-S nanocomposite and the interlayer concept have been suggested. For C-S composites, the structural parameters of the carbon hosts (i.e., pore size and porosity) proved to be very crucial to Li-S battery performance. In addition, a porous carbon interlayer inserted between the cathode and the separator to confine soluble polysulfides has been found effective in mitigating the polysulfide shuttling phenomena. However, most of approaches might not be suitable for mass production of cheap Li-S batteries. In this study, we propose a novel design of Li-S battery integrating a protective cathode incorporating a porous polysulfide adsorbent and a functional separator, which can be applied to current process and facilities. We focused on mitigating the polysulfide loss and further improving practical energy density of Li-S battery by investigating the electrochemical behavior of Li-S batteries under high sulfur loading conditions.