Siddharth Krishnan1 2 Tyler Ray2 Aaron Mickle3 Amit Ayer4 Philipp Gutruf2 Robert Gereau3 John Rogers2

1, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States
2, Northwestern University, Evanston, Illinois, United States
3, Washington University in St. Louis, St. Louis, Missouri, United States
4, Northwestern University, Chicago, Illinois, United States

Recent advances in mechanics and materials have allowed for a class of electronics that intimately couple to the soft, curvilinear surfaces of biological tissue. The low thermal mass, low contact resistances and ultrathin construction of these devices offer a compelling platform with which to thermally characterize living, biological systems. This talk summarizes a class of soft, bio-integrated electronics that combines low-power thermal actuation schemes with precise temperature sensing that has broad applications in dermatology, cardiovascular health, neurosurgery and neuroscience. Theoretical and experimental results uncover the physics of thermal transport in these systems and their versatility is illustrated through two target applications: (1) Skin mounted, ‘epidermal’ shunt failure monitors for hydrocephalus patients and (2) soft, implantable ‘cuffs’ for peripheral nerve interfaces that track nerve health.