David Mooney1

1, Harvard University, Cambridge, Massachusetts, United States

Dysfunction of the immune system underlies many diseases, and results from certain cancer therapies. However, strategies to effectively accelerate return of immune function and program disease-specific immune responses by manipulating stem cells and immune cells are at an early stage. We are creating biomaterials capable of concentrating, interrogating, and manipulating stem and immune cells ex vivo and in the body by controlling, in space and time, the interaction of the cells with various cues. The utility of this concept in the cancer therapies will be highlighted.