Since the development of colloidal methods of quantum dot (QD) synthesis in the early 1990s, there has been strong interest in the potential applications of these materials. The initial barrier to commercialisation was scale-up of the QD synthesis. Further, while early research focussed on cadmium-based II-VI QDs, concerns over the toxicity of these materials has led to the search for visible-emitting QDs free of cadmium and other toxic heavy metals. To address this, Nanoco Technologies Limited (Nanoco) has developed and patented a “molecular seeding” method of nanoparticle synthesis. Following over a decade of research, the method can be used to produce high quality heavy-metal free QDs in large volumes. While display products incorporating QD backlight units are now firmly established on the consumer market, we will discuss how QDs initially developed for displays are now being adapted and integrated into new applications, such as lighting, electroluminescent displays, and bio-imaging.