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Dean Ho1

1, University of California, Los Angeles, Los Angeles, California, United States

This lecture will highlight our recent clinical trial to validate a nanodiamond-embedded biomaterial [1]. We will discuss the broad spectrum of efficacy, safety, characterization, and other studies that bridged in vitro with preclinical and downstream in-human studies. To provide an outlook for upcoming clinical studies, this talk will also highlight our work in augmented AI to develop globally optimized nanodiamond-modified therapy. Pairing nanodiamond platforms with augmented AI will lead to major advances in drug development and markedly improve response rates for a broad spectrum of disorders. This talk will also highlight our recent clinical trials using these powerful combination therapy optimization technologies and how they will usher in a new era of nanomedicine-based treatment [2].

1. Lee et al., Proceedings of the National Academy of Sciences, 2017
2. Zarrinpar et al., Science Translational Medicine, 2016

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