Molly Stevens1

1, Imperial College London, London, , United Kingdom

This talk will provide an overview of our recent developments in the design of nanomaterials for ultrasensitive biosensing. Bio-responsive nanomaterials are of growing importance with potential applications including drug delivery, diagnostics and tissue engineering (1). Using enzyme-mediated signal readouts we have developed a suite of nanoparticle based ultrasensitive biosensing approaches as well as a cell/tissue-interfacing nanoneedle platform (2). We are applying these biosensing approaches both in high throughput drug screening and to diagnose diseases ranging from cancer to global health applications.
[1] Stevens MM, George JH, Exploring and engineering the cell surface interface., Science, 2005, Vol:310, Pages:1135-1138.
[2] Howes PD, Chandrawati R, Stevens MM, 2014, Colloidal nanoparticles as advanced biological sensors, Science, 2013, Vol:346, DOI: 10.1126/science.1247390.